I haven't ridden the new Vamoots CR, but other than the name it appears to be virtually identical to the former Compact model. The one difference in geometry is that every size CR has a slightly taller headtube (typically 4 -5 mm) than the Compact, which for most people is probably not a bad thing. I don't believe that Moots tinkered with the tubesets, but Jon or someone from Moots could confirm that (why mess with perfection?).
Given that it is basically the same as the Compact, it is very much a tried-and-true design. I find that there is a very similar fell in terms of ride quality and stiffness between the Psychlo-X and Moots' road bikes. If you love the way your Psychlo-X rides (especially stiffness, road feel, etc.), I'm almost certain that you will love the CR.